DBX Demineralized Bone Matrix


DBX Demineralized Bone Matrix (DBM) is an allograft bone void filler that is processed by the Musculoskeletal Transplant Foundation (MTF). Synthes has partnered exclusively with MTF for over 10 years to provide high quality tissue for patients.

DBX DBM is an osteoconductive bone void filler which has been shown to have osteoinductive potential* in a validated athymic mouse model. Each finished lot of tissue is tested for osteoinductive potential prior to release for clinical use. DBX DBM is ideal for a variety of applications within the cleared indications.​​​​​​​​​​​​​​​​​​​​​​​​​​​​


Key Features & Benefits

  • Available as Putty, Mix, Strips and Injectable Putty
  • Demonstrated bone formation – high bone content, osteoinductive potential, histologic verification
  • Inert biocompatible carrier, pH-balanced, nonhemolytic
  • Exemplary safety record
  • Resists movement under irrigation, maintains physical integrity
  • Excellent handling characteristics
*It is unknown how the osteoinductive potential, measured in the athymic mouse model or the alkaline phosphatase assay, will correlate with clinical performance in human subjects.

Spine Indications**

DBX Putty, Mix and Inject

  • Intended for use as a demineralized bone matrix for voids or gaps that are not intrinsic to the stability of the bony structure.
  • Indicated for treatment of surgically created osseous defects or osseous defects created from traumatic injury.
    1. DBX Putty, Mix and Inject may be used in the posterolateral spine.
    2. DBX Putty, Mix and Inject can be used with bone marrow.
    3. DBX Putty and Inject can be used as an extender in the spine with autograft or allograft.

DBX Strip

  • Indicated as a bone void filler for treatment of surgically created osseous voids or gaps that are not intrinsic to the stability of the bony structure.
  • Can be used in the posterolateral spine for posterolateral fusion.
  • When used for posterolateral spine fusion, may be used with autograft.

** Please refer to the package insert for a complete list of indications, contraindications, precautions and warnings.

For further information on Synthes products, please contact your local Synthes representative.


 DBX Demineralized Bone Matrix - Spine


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